Home › Venues › SUBSTANCE SUBSTANCE Tickets Find places to see live music. SUBSTANCE Concert Tickets & Calendar Thu Jan 1, 2026 Tchami SUBSTANCE Las Vegas, NV Tickets & Info Calendar Hotels & Lodging Near SUBSTANCE About the Venue SUBSTANCE At-a-Glance Capacity 1,267Address450 Fremont StreetLas Vegas, NV 89101United States Map & Directions Website substancelv.com/ Next Event Tchami Jan 1, 2026 Advertisement